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List of substances for condition Group: Liver

All Human Animal Risk/Association ReviewRows: 607

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Curcumin 📋✍⛔38669311The Potential Mechanism of the Anti-Liver Fibrotic Effect of Curcumin in the Gut-Liver Axis
Ginsenosides 📋✍⛔38708102Ameliorative effect of total ginsenosides from heat-treated fresh ginseng against cyclophosphamide-induced liver injury in mice
Resveratrol 📋✍⛔38262562Calorie restriction mimetic, resveratrol, attenuates hepatic ischemia and reperfusion injury through enhancing efferocytosis of macrophages via AMPK/STAT3/S1PR1 pathway
Silymarin 📋✍⛔38726410Silymarin: Unveiling its pharmacological spectrum and therapeutic potential in liver diseases-A comprehensive narrative review
Berberine 📋✍⛔38723878Berberine ameliorates nonalcoholic fatty liver disease-induced bone loss by inhibiting ferroptosis
Melatonin 📋✍⛔38618269Melatonin Mitigates the Progression of Chemically Induced Hepatocellular Carcinoma in Rats via Targeting Wnt/Β-Catenin Pathway, and Small Noncoding miR-let-7b
Vitamin D3 📋✍⛔38732118Vitamin D and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Novel Mechanistic Insights
Quercetin 📋✍⛔38501770Ethanol-Induced Hepatic Ferroptosis Is Mediated by PERK-Dependent MAMs Formation: Preventive Role of Quercetin
EGCG 📋✍⛔38607257Tea Polyphenol Epigallocatechin Gallate Protects Against Nonalcoholic Fatty Liver Disease and Associated Endotoxemia in Rats via Modulating Gut Microbiota Dysbiosis and Alleviating Intestinal Barrier Dysfunction and Related Inflammation
Metformin 📋✍⛔38413541Identification of glucose-independent and reversible metabolic pathways associated with anti-proliferative effect of metformin in liver cancer cells
N-Acetyl Cysteine 📋✍⛔38540289The Use and Potential Benefits of N-Acetylcysteine in Non-Acetaminophen Acute Liver Failure: An Etiology-Based Review
Vitamin E 📋✍⛔38549357Effect of vitamin E supplementation on bilirubin levels in infants with hyperbilirubinemia: a double-blind randomized clinical trial
Vitamin C 📋✍⛔38635545Potassium affects the association between dietary intake of vitamin C and NAFLD among adults in the United States
Lycopene 📋✍⛔38544357Lycopene Alleviates Endoplasmic Reticulum Stress in Steatohepatitis through Inhibition of the ASK1-JNK Signaling Pathway
Ginseng 📋✍⛔38465218Pharmacological potential of ginseng and ginsenosides in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
Omega-3 Fatty Acids 📋✍⛔38139055The Ameliorating Effects of n-3 Polyunsaturated Fatty Acids on Liver Steatosis Induced by a High-Fat Methionine Choline-Deficient Diet in Mice
Silibinin 📋✍ 38675395Silibinin's Effects against Methotrexate-Induced Hepatotoxicity in Adjuvant-Induced Arthritis Rat Model
Astragalosides 📋✍⛔38521426Astragaloside IV ameliorates cisplatin-induced liver injury by modulating ferroptosis-dependent pathways
Luteolin 📋✍⛔38500179The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages
Apigenin 📋✍⛔38619972Apigenin Suppresses MED28-Mediated Cell Growth in Human Liver Cancer Cells
Astaxanthin 📋✍⛔38692895Astaxanthin, Haematococcus pluvialis and Haematococcus pluvialis Residue Alleviate Liver Injury in D-Galactose-induced Aging Mice through Gut-liver Axis
Fucoidan 📋✍⛔38710247Fucoidan from Apostichopus japonicus ameliorates alcoholic liver disease by regulating gut-liver axis homeostasis
Goji Berry 📋✍⛔38675458Protective Effects of Lycium ruthenicum Murray against Acute Alcoholic Liver Disease in Mice via the Nrf2/HO-1/NF-κB Signaling Pathway
Hesperidin 📋✍⛔38294790Hesperidin Protects Against High-Fat Diet-Induced Lipotoxicity in Rats by Inhibiting Pyroptosis
Naringenin 📋✍⛔38582338Naringenin inhibits APAP-induced acute liver injury through activating PPARA-dependent signaling pathway
Genistein 📋✍⛔38504590Active Components of Pueraria lobata through the MAPK/ERK Signaling Pathway Alleviate Iron Overload in Alcoholic Liver Disease
Thymoquinone 📋 ⛔38504479Thymoquinone protects thioacetamide-induced chronic liver injury by inhibiting TGF-β1/Smad3 axis in rats
Puerarin 📋✍⛔38674860Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice
Sulforaphane 📋✍⛔38721140Sulforaphane protects against LPS-induced liver injury in mice by antagonizing oxidative stress and apoptosis through AMPK activation
Dihydromyricetin 📋✍⛔38532480Dihydromyricetin ameliorates hepatic steatosis and insulin resistance via AMPK/PGC-1α and PPARα-mediated autophagy pathway
Astragalus Root 📋✍⛔38211994[Protective effect and mechanism of Astragalus membranaceus and Angelica sinensis compatibility against triptolide-induced hepatotoxicity by regulating Keap1/Nrf2/PGC-1α]
Pterostilbene 📋✍⛔38414698Influence of Pterostilbene on Gene Expression in Liver Cancer: An In Silico Analysis
Baicalin 📋✍⛔38621980[Baicalin induces ferroptosis in HepG2 cells by inhibiting ROS-mediated PI3K/Akt/FoxO3a signaling pathway]
Schisandra 📋✍⛔38585559A combined extract containing Schisandra chinensis (SCE) reduced hepatic triglyceride accumulation in rats fed a high-sucrose diet
Reishi Mushrooms 📋✍⛔38451046Sporoderm-broken spores of Ganoderma lucidum modulate hepatoblastoma malignancy by regulating RACK1-mediated autophagy and tumour immunity
Ellagic Acid 📋✍⛔38671932Unlocking the Therapeutic Potential of Ellagic Acid for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
Gallic Acid 📋 ⛔37993853Gallic acid rescues uranyl acetate induced-hepatic dysfunction in rats by its antioxidant and cytoprotective potentials
Nigella Sativa 📋✍⛔37110159Efficacy Confirmation Test of Black Cumin ( Nigella sativa L.) Seeds Extract Using a High-Fat Diet Mouse Model
Kaempferol 📋✍⛔38493774Kaempferol ameliorated alcoholic hepatitis through improving intestinal barrier function by targeting miRNA-155 signaling
Zinc 📋✍⛔38012749The effects of zinc supplementation on the metabolic factors in patients with non-alcoholic fatty liver disease: a randomized, double-blinded, placebo-controlled clinical trial
Anthocyanins 📋✍⛔38290991Blueberry anthocyanins improve liver fibrosis by regulating NCOA4 ubiquitination through TRIM7 to affect ferroptosis of hepatic stellate cells
Glycyrrhizic Acid 📋✍⛔38700384Glycyrrhizic acid attenuates the malignant biological properties of nonalcoholic fatty liver disease-related hepatocellular carcinoma
Lipoic Acid 📋✍⛔38245790(+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease
Indian Gooseberry 📋 ⛔37573920Protective effects of Emblica officinalis polysaccharide against lead induced liver injury in mice model
Moringa Oleifera 📋✍⛔38379081Hepatoprotective Effect of Moringa Oil on Rats under Fungicide Toxicity
Mulberry 📋 ⛔38707917Mulberry leaf extract inhibits obesity and protects against diethylnitrosamine-induced hepatocellular carcinoma in rats
Chrysin 📋✍⛔38432408Targeting SIRT1, NLRP3 inflammasome, and Nrf2 signaling with chrysin alleviates the iron-triggered hepatotoxicity in rats
Dandelion 📋✍⛔36078142Apigetrin Promotes TNFα-Induced Apoptosis, Necroptosis, G2/M Phase Cell Cycle Arrest, and ROS Generation through Inhibition of NF-κB Pathway in Hep3B Liver Cancer Cells
Ginkgo Biloba 📋✍⛔38727268L-carnitine and Ginkgo biloba Supplementation In Vivo Ameliorates HCD-Induced Steatohepatitis and Dyslipidemia by Regulating Hepatic Metabolism
Nobiletin 📋✍ 38563051Nobiletin alleviates methotrexate-induced hepatorenal toxicity in rats
Andrographolide 📋 38467318Inhibition of hepatocellular carcinoma cell proliferation through regulation of the cell cycle, AGE RAGE, and leptin signaling pathways by a compound formulation comprised of andrographolide, wogonin, and oroxylin a derived from Andrographis Paniculata(Burm.f.) Nees
Fisetin 📋✍⛔38708470Fisetin ameliorates methotrexate induced liver fibrosis
Green Tea Polyphenols 📋✍⛔37753369Green tea polyphenols alleviate di-(2-ethylhexyl) phthalate-induced liver injury in mice
L-Carnitine 📋✍⛔38727268L-carnitine and Ginkgo biloba Supplementation In Vivo Ameliorates HCD-Induced Steatohepatitis and Dyslipidemia by Regulating Hepatic Metabolism
Salidroside 📋 38333759Salidroside alleviates LPS-induced liver injury and inflammation through SIRT1- NF-κB pathway and NLRP3 inflammasome
Taurine 📋✍⛔38681990Taurine attenuates activation of hepatic stellate cells by inhibiting autophagy and inducing ferroptosis
Grape Seed extract 📋✍⛔38500515Grape seed proanthocyanins protect fluoride-induced hepatotoxicity via the Nrf2 signaling pathway in male rats
Baicalein 📋✍⛔38727775Hepatoprotective effects of baicalein against liver ischemia-reperfusion injury and partial hepatectomy in a rat model
Naringin 📋✍⛔38054638Naringin Protects against Non-Alcoholic Fatty Liver Disease by Promoting Autophagic Flux and Lipophagy
TUDCA 📋✍⛔36795945Potential therapeutic action of Tauroursodeoxycholic acid against cholestatic liver injury via hepatic Fxr/Nrf2 and CHOP-DR5-caspase-8 pathway
Chlorogenic Acid 📋✍⛔38708558Chlorogenic acid and its isomers attenuate NAFLD by mitigating lipid accumulation in oleic acid-induced HepG2 cells and high-fat diet- fed zebrafish
Coffee 📋✍⛔38201969Different Associations of Coffee Consumption with the Risk of Incident Metabolic Dysfunction-Associated Steatotic Liver Disease and Advanced Liver Fibrosis
Probiotics 📋✍⛔38072206The Synbiotic Combination of probiotics and inulin Improves NAFLD though Modulating Gut Microbiota
Selenium 📋✍⛔38633147Ameliorative effects of berberine and selenium against paracetamol-induced hepatic toxicity in rats
Licorice Root 📋✍⛔37081966Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis
Pomegranate 📋 ⛔38661445Pomegranate supplementation alleviates dyslipidemia and the onset of non-alcoholic fatty liver disease in Wistar rats by shifting microbiota and producing urolithin-like microbial metabolites
Blueberry 📋✍⛔37128328Blueberry and cranberry extracts mitigate CCL4-induced liver damage, suppressing liver fibrosis, inflammation and oxidative stress
Dihydroartemisinin 📋 38713259Target prediction and potential application of dihydroartemisinin on hepatocarcinoma treatment
Cannabidiol 📋✍⛔38711461Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways
CoQ10 📋✍⛔37701221The effect of coenzyme Q10 supplementation on liver enzymes: A systematic review and meta-analysis of randomized clinical trials
Diosmin 📋✍⛔38234671Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats
Gingerol 📋✍ 385655696-Gingerol attenuates hepatic ischemia/reperfusion injury through regulating MKP5-mediated P38/JNK pathway
Medicinal Plants 📋 38464716The additive effect of herbal medicines on lifestyle modification in the treatment of non-alcoholic fatty liver disease: a systematic review and meta-analysis
Rutin 📋✍⛔38581023The ameliorating effect of Rutin on hepatotoxicity and inflammation induced by the daily administration of vortioxetine in rats
Galangin 📋 35889537In Silico Target Identification of Galangin, as an Herbal Flavonoid against Cholangiocarcinoma
Paeoniflorin 📋 38489890Paeoniflorin promotes PPARγ expression to suppress HSCs activation by inhibiting EZH2-mediated histone H3K27 trimethylation
Schisandrins 📋 38500179The combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages
Garlic 📋✍⛔38223588Garlic supplementation for the treatment of chronic liver disease: a meta-analysis of randomized controlled trials
Nicotinamide Riboside 📋✍⛔38729053Integrated transcriptome and metabolome study reveal the therapeutic effects of nicotinamide riboside and nicotinamide mononucleotide on nonalcoholic fatty liver disease
Salvianolic Acid 📋 38674860Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice
UDCA 📋✍⛔38643542A high-dose of ursodeoxycholic acid treatment alleviates liver inflammation by remodeling gut microbiota and bile acid profile in a mouse model of non-alcoholic steatohepatitis
Crocin 📋✍⛔37627094Combining Crocin and Sorafenib Improves Their Tumor-Inhibiting Effects in a Rat Model of Diethylnitrosamine-Induced Cirrhotic-Hepatocellular Carcinoma
Ferulic Acid 📋✍⛔38293309Ferulic acid interventions ameliorate NDEA-CCl4-induced hepatocellular carcinoma via Nrf2 and p53 upregulation and Akt/PKB-NF-κB-TNF-α pathway downregulation in male Wistar rats
Fish Oil 📋✍⛔38325844Fish oil consumption prevents hepatic lipid accumulation induced by high-cholesterol feeding in obese KK mice
Pomegranate Peel extract 📋✍⛔37605174Pomegranate (Punica granatum L.) peel extract ameliorates metabolic syndrome risk factors in patients with non-alcoholic fatty liver disease: a randomized double-blind clinical trial
Red Sage 📋✍⛔38636259Salvia miltiorrhiza polysaccharide mitigates AFB1-induced liver injury in rabbits
Angelica 📋✍⛔38211994[Protective effect and mechanism of Astragalus membranaceus and Angelica sinensis compatibility against triptolide-induced hepatotoxicity by regulating Keap1/Nrf2/PGC-1α]
Carvacrol 📋✍⛔37351047Carvacrol Exerts Anti-Inflammatory, Anti-Oxidative Stress and Hepatoprotective Effects Against Diclofenac-Induced Liver Injury in Male Rats
Licochalcones 📋 38284775The Ameliorative Role of Lico A on Aflatoxin B1-Triggered Hepatotoxicity Partially by Activating Nrf2 Signal Pathway
Allicin 📋✍⛔38728949Allicin regulates Sestrin2 ubiquitination to affect macrophage autophagy and senescence, thus inhibiting the growth of hepatoma cells
Fucoxanthin 📋✍⛔38669300Molecular Mechanisms of Fucoxanthin in Alleviating Lipid Deposition in Metabolic Associated Fatty Liver Disease
Piperine 📋✍⛔38547097Piperine alleviates nonalcoholic steatohepatitis by inhibiting NF-κB-mediated hepatocyte pyroptosis
Spirulina 📋✍⛔36432871Spirulina platensis Ameliorates Oxidative Stress Associated with Antiretroviral Drugs in HepG2 Cells
Betaine 📋✍⛔38713257Modulation of the Nrf-2 and HO-1 signalling axis is associated with Betaine's abatement of fluoride-induced hepatorenal toxicities in rats
Caffeine 📋✍⛔38495344Caffeine in Hepatocellular Carcinoma: Cellular Assays, Animal Experiments, and Epidemiological Investigation
Docosahexaenoic Acid 📋✍⛔38680033Docosahexaenoic Acid Supplementation for Neonatal Hyperbilirubinemia: A Double-Blind, Randomized Clinical Trial
Magnesium 📋✍⛔38056458Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism
Tanshinone 📋 38621946[Tanshinone â…¡_A inhibits ferroptosis via Nrf2 signaling pathway to protect liver in rats of non-alcoholic fatty liver disease]
Wormwood 📋✍⛔38162595Protective impacts of Artemisia annua against hepatic toxicity induced by gentamicin
Asiatic Acid 📋 37272388Asiatic acid ameliorates rifampicin and isoniazid-induced liver injury in vivo by regulating sphingolipid metabolism and mitogen-activated protein kinase signaling pathways
BCAA 📋✍⛔37836474Use of Branched-Chain Amino Acids as a Potential Treatment for Improving Nutrition-Related Outcomes in Advanced Chronic Liver Disease
Emodin 📋 ⛔38284886Prepared radix polygoni multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition
Geniposide 📋 38069009Mixture of Peanut Skin Extract, Geniposide, and Isoquercitrin Improves the Hepatic Lipid Accumulation of Mice via Modification of Gut Microbiota Homeostasis and the TLR4 and AMPK Signaling Pathways
Maitake Mushrooms 📋 ⛔37049720Synergistic Antitumor Effect of Grifola frondose Polysaccharide-Protein Complex in Combination with Cyclophosphamide in H22 Tumor-Bearing Mice
Skullcap 📋✍⛔38616754Network Pharmacology, Molecular Docking Analysis and Molecular Dynamics Simulation of Scutellaria baicalensis in the Treatment of Liver Fibrosis
Wogonin 📋✍⛔38467318Inhibition of hepatocellular carcinoma cell proliferation through regulation of the cell cycle, AGE RAGE, and leptin signaling pathways by a compound formulation comprised of andrographolide, wogonin, and oroxylin a derived from Andrographis Paniculata(Burm.f.) Nees
Chlorella 📋✍⛔38704764Therapeutic potential of Lactobacillus casei and Chlorella vulgaris in high-fat diet-induced non-alcoholic fatty liver disease (NAFLD)-associated kidney damages: a stereological study
Dihydroquercetin 📋 38552433Dihydroquercetin improves experimental acute liver failure by targeting ferroptosis and mitochondria-mediated apoptosis through the SIRT1/p53 axis
Honokiol 📋 38402928The natural compounds, Magnolol or Honokiol, promote adipose tissue browning and resist obesity through modulating PPARα/γ activity
Micronutrients 📋 ⛔38703282A comprehensive review of phytoconstituents in liver cancer prevention and treatment: targeting insights into molecular signaling pathways
Acetyl-L-Carnitine 📋✍⛔37511276Acetyl-L-Carnitine and Liposomal Co-Enzyme Q10 Attenuate Hepatic Inflammation, Apoptosis, and Fibrosis Induced by Propionic Acid
Amygdalin 📋✍⛔37726740Hepatocellular Carcinoma cells: activity of Amygdalin and Sorafenib in Targeting AMPK /mTOR and BCL-2 for anti-angiogenesis and apoptosis cell death
Bee Propolis 📋✍⛔36963888Clinical effectiveness of α-lipoic acid, myo-inositol and propolis supplementation on metabolic profiles and liver function in obese patients with NAFLD: A randomized controlled clinical trial
Fenugreek 📋✍⛔35064405Hepatoprotective effect of Trigonella foenum graecum against ethanol-induced cell death in human liver cells (HepG2 and Huh7)
Green Tea 📋✍⛔38370081Long-term drinking of green tea combined with exercise improves hepatic steatosis and obesity in male mice induced by high-fat diet
Hawthorn 📋✍⛔38601914A study on the treatment effects of Crataegus pinnatifida polysaccharide on non-alcoholic fatty liver in mice by modulating gut microbiota
Icaritin 📋 38431053Icaritin activates p53 and inhibits aerobic glycolysis in liver cancer cells
Mangiferin 📋 ⛔37444207Mangiferin for the Management of Liver Diseases: A Review
Rosmarinic Acid 📋✍ 38631488Rosmarinic acid alleviates toosendanin-induced liver injury through restoration of autophagic flux and lysosomal function by activating JAK2/STAT3/CTSC pathway
Royal Jelly 📋✍⛔38281144Research progress on rat model of drug-induced liver injury established by nonsteroidal anti-inflammatory drug (celecoxib) and royal jelly ameliorative effect
Sea Buckthorn 📋✍⛔37833431Hippophae rhamnoides reverses decreased CYP2D6 expression in rats with BCG-induced liver injury
Aged Garlic 📋✍⛔36856009Aged Garlic Extract Prevents Alcohol-Induced Cytotoxicity through Induction of Aldehyde Dehydrogenase 2 in the Liver of Mice
Arctigenin 📋 38679116Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice
Aspirin 📋 ⛔38049630Hepatoprotective effects of aspirin on diethylnitrosamine-induced hepatocellular carcinoma in rats by reducing inflammation levels and PD-L1 expression
Barberry 📋✍⛔35958317Berbamine and thymoquinone exert protective effects against immune-mediated liver injury via NF-κB dependent pathway
Carnosic Acid 📋 36577209Carnosic acid suppressed the formation of NETs in alcoholic hepatosteatosis based on P2X7R-NLRP3 axis
Coptis Chinensis 📋 ⛔38103844Integrating transcriptomics and network pharmacology to reveal the mechanisms of total Rhizoma Coptidis alkaloids against nonalcoholic steatohepatitis
Diosgenin 📋 38458224Therapeutic Potential of Diosgenin in Amelioration of Carbon Tetrachloride-Induced Murine Liver Injury
Glycyrrhetinic Acid 📋 38244730Ursodeoxycholic acid and 18β-glycyrrhetinic acid alleviate ethinylestradiol-induced cholestasis via downregulating RORγt and CXCR3 signaling pathway in iNKT cells
Grape 📋 ⛔37511015Synergistic Effects of Vitis vinifera L. and Centella asiatica against CCl4-Induced Liver Injury in Mice
Mangosteen 📋✍⛔35597781Bioactive xanthones, benzophenones and biphenyls from mangosteen root with potential anti-migration against hepatocellular carcinoma cells
Phytochemicals 📋 38283267Evidence-based herbal treatments in liver diseases
Withaferin A 📋 38537439Withaferin A, a natural thioredoxin reductase 1 (TrxR1) inhibitor, synergistically enhances the antitumor efficacy of sorafenib through ROS-mediated ER stress and DNA damage in hepatocellular carcinoma cells
Beta-Sitosterol 📋✍⛔38063438β-Sitosterol suppresses hepatocellular carcinoma growth and metastasis via FOXM1-regulated Wnt/β-catenin pathway
Capsaicin 📋✍⛔36938442Capsaicin protects against septic acute liver injury by attenuation of apoptosis and mitochondrial dysfunction
Chokeberry 📋✍⛔36344052Aronia melanocarpa polysaccharide ameliorates liver fibrosis through TGF-β1-mediated the activation of PI3K/AKT pathway and modulating gut microbiota
Gardenia 📋 ⛔38090678Gardenia Iridoid Glucosides Protect Against α-Naphthalene Isothiocya-Nate-Induced Cholestatic Rats Through Activation of the FXR-SHP Signaling Pathway
Ginger 📋✍⛔37817641The Effects of Ginger ( Zingiber Officinale Roscoe) on Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blinded Placebo-Controlled Clinical Trial
Hydroxytyrosol 📋 38680105Hydroxytyrosol ameliorates stress-induced liver injury through activating autophagy via HDAC1/2 inhibition
Kiwifruit 📋✍⛔38027882Exploring the anticancer potential of Actinidia chinensis Planch root extracts ( acRoots) on hepatocellular carcinoma: A molecular mechanism study
Oleuropein 📋 38436159Oleuropein, a phenolic component of Olea europaea L. ameliorates CCl4-induced liver injury in rats through the regulation of oxidative stress and inflammation
Peony 📋 ⛔38599475Paeonia lactiflora Pall. ameliorates acetaminophen-induced oxidative stress and apoptosis via inhibiting the PKC-ERK pathway
Polyphenols 📋 38625672Liver cancer wars: plant-derived polyphenols strike back
Saffron 📋✍⛔38055395Saffron reduces the liver fibrosis in mice by inhibiting the JAK/STAT3 pathway
Walnut 📋 ⛔37839834Polysaccharide from walnut green husk alleviates liver inflammation and gluconeogenesis dysfunction by altering gut microbiota in ochratoxin A-induced mice
Artichoke 📋✍⛔37891925Evaluation of the Protective and Regenerative Properties of Commercially Available Artichoke Leaf Powder Extract on Plasma and Liver Oxidative Stress Parameters
Cranberry 📋✍⛔37128328Blueberry and cranberry extracts mitigate CCL4-induced liver damage, suppressing liver fibrosis, inflammation and oxidative stress
Hesperetin 📋 38007145Protective role of hesperetin in sorafenib-induced hepato- and neurotoxicity in mice via modulating apoptotic pathways and mitochondrial reprogramming
Isoliquiritigenin 📋 38671579Isoliquiritigenin limits inflammasome activation of macrophage via docking into Syk to alleviate murine non-alcoholic fatty liver disease
NMN 📋✍⛔38729053Integrated transcriptome and metabolome study reveal the therapeutic effects of nicotinamide riboside and nicotinamide mononucleotide on nonalcoholic fatty liver disease
Ollive Leaf extract 📋✍⛔38385474The hepatoprotective potentials of Olea europaea L. leaves against carbon tetrachloride-induced hepatic injury in rats
Polydatin 📋✍ 36672157Polydatin Inhibits Hepatocellular Carcinoma Cell Proliferation and Sensitizes Doxorubicin and Cisplatin through Targeting Cell Mitotic Machinery
Punicalagin 📋✍⛔36324170Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model
Raspberry 📋✍⛔37513533Prebiotics Together with Raspberry Polyphenolic Extract Mitigate the Development of Nonalcoholic Fatty Liver Diseases in Zucker Rats
Vitamin A 📋✍⛔38253816Association between dietary vitamin A intake from different sources and non-alcoholic fatty liver disease among adults
Acai Berry 📋✍⛔33621858Dietary anthocyanin-rich extract of açai protects from diet-induced obesity, liver steatosis, and insulin resistance with modulation of gut microbiota in mice
Apple Polyphenols 📋 ⛔38055797Preventive Effects of Apple Polyphenol Extract on High-Fat-Diet-Induced Hepatic Steatosis Are Related to the Regulation of Hepatic Lipid Metabolism, Autophagy, and Gut Microbiota in Aged Mice
Atractylodes 📋✍⛔38663104The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats
Carotenoids 📋✍⛔38134087Association between carotenoid intake and metabolic dysfunction-associated fatty liver disease among US adults: A cross-sectional study
Catechins 📋 35738327Catechins protect against acrylamide- and glycidamide-induced cellular toxicity via rescuing cellular apoptosis and DNA damage
Cordycepin 📋 38589021Cordycepin Enhanced Therapeutic Potential of Gemcitabine against Cholangiocarcinoma via Downregulating Cancer Stem-Like Properties
Echinacea 📋✍⛔38459283Echinacea purpurea root extract mitigates hepatotoxicity, genotoxicity, and ultrastructural changes induced by hexavalent chromium via oxidative stress suppression
Escin 📋✍⛔36905866Aescin can alleviate NAFLD through Keap1-Nrf2 by activating antioxidant and autophagy
Fo-Ti Root 📋✍⛔38284886Prepared radix polygoni multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition
Food 📋 37571287You Are What You Eat: A Review on Dietary Interventions for Treating Pediatric Nonalcoholic Fatty Liver Disease
Formononetin 📋 38185065Formononetin promotes fatty acid β-oxidation to treat non-alcoholic steatohepatitis through SIRT1/PGC-1α/PPARα pathway
Frankincense 📋✍⛔37866446Guided discovery of hepatoprotective polyhydroxy cembrane-type diterpenoids from the gum resin of Boswellia carterii by MS/MS molecular networking
Inulin 📋✍⛔38333950Effects of Oat β-Glucan and Inulin on Alleviation of Nonalcoholic Steatohepatitis Aggravated by Circadian Disruption in C57BL/6J Mice
Kudzu Root 📋✍⛔38008472Structural elucidation of an active polysaccharide from Radix Puerariae lobatae and its protection against acute alcoholic liver disease
Milk Thistle 📋✍⛔36788749Combinatorial treatment with Silybum marianum essential oil enhances the therapeutic efficacy of a 5-fluorouracil base therapy for hepatocellular carcinoma
Myricetin 📋 ⛔35707887The protective effects of myricetin against acute liver failure via inhibiting inflammation and regulating oxidative stress via Nrf2 signaling
Pine Bark 📋✍⛔35745592Protective Effect of Pycnogenol against Methotrexate-Induced Hepatic, Renal, and Cardiac Toxicity: An In Vivo Study
Poria Mushrooms 📋✍ 38507458Poria cocos polysaccharides improve alcoholic liver disease by interfering with ferroptosis through NRF2 regulation
Zingerone 📋 36837786Neonatal Orally Administered Zingerone Attenuates Alcohol-Induced Fatty Liver Disease in Experimental Rat Models
Apple 📋 ⛔32326503Hepatoprotective Effects of Standardized Extracts from an Ancient Italian Apple Variety (Mela Rosa dei Monti Sibillini) against Carbon Tetrachloride (CCl 4)-Induced Hepatotoxicity in Rats
Ashwagandha 📋✍⛔37663806Protective impacts of Withania somnifera leaf extract from Taif area against diclofenac induced hepato-renal toxicity: role of antioxidants, inflammation, apoptosis, and anti-oxidative stress biomarkers
Bee Venom 📋✍⛔38109225Use of bee venom in preventive medicine: An experimental hepatic encephalopathy study in rats
Beta-Carotene 📋✍⛔37914264β-Carotene Protects Mice against Lipopolysaccharide and D-Galactosamine Induced Acute Liver Injury via Regulation of NF-κB, MAPK, and Nrf2 Signaling
Beta-Cryptoxanthin 📋 35464265Xanthophyll β-cryptoxanthin treatment inhibits hepatic steatosis without altering vitamin A status in β-carotene 9',10'-oxygenase knockout mice
Black Tea 📋✍⛔36742427Compound dark tea ameliorates obesity and hepatic steatosis and modulates the gut microbiota in mice
Calycosin 📋 37506138Calycosin inhibits hepatocyte apoptosis in acute liver failure by suppressing the TLR4/NF-κB pathway: An in vitro study
Cinnamon 📋✍⛔37655003Hepatic regenerative response to long-term consumption of cinnamon-rich diet in aged rats
Daidzein 📋✍⛔37759583Protective Effect of Daidzein against Diethylnitrosamine/Carbon Tetrachloride-Induced Hepatocellular Carcinoma in Male Rats
Eicosapentaenoic Acid 📋✍⛔37265154Selenium ameliorated oxidized fish oil-induced lipotoxicity via the inhibition of mitochondrial oxidative stress, remodeling of Usp4-mediated deubiquitination and stabilization of Pparα
Flavonoids 📋 ⛔38487354An overview of anti-Hepatitis B virus flavonoids and their mechanisms of action
Ginger extract 📋✍⛔33338743Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/ inflammation pathway
Gotu Kola 📋✍⛔37576314A herb mixture to ameliorate non-alcoholic fatty liver in rats fed a high-fat diet
Hyperoside 📋 37923159Hyperoside attenuates carbon tetrachloride-induced hepatic fibrosis via the poly(ADP-ribose)polymerase-1-high mobility group protein 1 pathway
Myrrh 📋✍⛔37719039Water extract of frankincense and myrrh inhibits liver cancer progression and epithelial‑mesenchymal transition through Wnt/β‑catenin signaling
Olive Oil 📋✍⛔37960329High Extra Virgin Olive Oil Consumption Is Linked to a Lower Prevalence of NAFLD with a Prominent Effect in Obese Subjects: Results from the MICOL Study
Pomegranate Seed extract 📋 ⛔38065332Pomegranate Seed Oil Mitigates Liver and Kidney Damage in an Experimental Colitis Model: Modulation of NF-κB Activation and Apoptosis
Shogaol 📋 382573326-Shogaol Ameliorates Liver Inflammation and Fibrosis in Mice on a Methionine- and Choline-Deficient Diet by Inhibiting Oxidative Stress, Cell Death, and Endoplasmic Reticulum Stress
Tangeretin 📋 37517432Tangeretin and 4'-demethyltangeretin prevent damage to mouse hepatocytes from oxidative stress by activating the Nrf2-related antioxidant pathway via an epigenetic mechanism
Ursolic Acid 📋✍⛔38623614Ursolic acid targets secreted phosphoprotein 1 to regulate Th17 cells against non-alcoholic fatty liver disease
Acacetin 📋 38571642Mechanism of acacetin regulating hepatic stellate cell apoptosis based on network pharmacology and experimental verification
Aloe Vera 📋✍⛔38467965Aloe vera gel relieves cadmium triggered hepatic injury via antioxidative, anti-inflammatory, and anti-apoptotic routes
Bergamot 📋✍⛔32849284Randomized Clinical Trial: Bergamot Citrus and Wild Cardoon Reduce Liver Steatosis and Body Weight in Non-diabetic Individuals Aged Over 50 Years
Blackcurrant 📋✍⛔32466275Blackcurrant ( Ribes nigrum) Extract Prevents Dyslipidemia and Hepatic Steatosis in Ovariectomized Rats
Bromelain 📋✍⛔37269556Bromelain mitigates liver fibrosis via targeting hepatic stellate cells in vitro and in vivo
Date 📋 ⛔35459999Ruthana date extract inhibited proliferation of human hepatocellular carcinoma (HepG2) cells by modulation of BAX gene
Eugenol 📋 35508252Eugenol alleviated nonalcoholic fatty liver disease in rat via a gut-brain-liver axis involving glucagon-like Peptide-1
Fig 📋 ⛔35874505Ameliorative or corrective effects of Fig " Ficus carica" extract on nickel-induced hepatotoxicity in Wistar rats
Glabridin 📋 37714449Glabridin ameliorates intracellular events caused by palmitic acid and alcohol in mouse hepatocytes and fast food diet and alcohol -induced steatohepatitis and fibrosis in C57BL/6J mice model
Lactobacillus plantarum 📋 ⛔38126998Lactobacillus plantarum ST-III culture supernatant protects against acute alcohol-induced liver and intestinal injury
Lingonberry 📋 ⛔35802745Inhibitory effect of lingonberry extract on HepG2 cell proliferation, apoptosis, migration, and invasion
Oleanolic Acid 📋 38387275Oleanolic acid inhibits hypoxic tumor-derived exosomes-induced premetastatic niche formation in hepatocellular carcinoma by targeting ERK1/2-NFκB signaling
Rapamycin 📋✍ 38548510Beneficial Effect of Rapamycin on Liver Fibrosis in a Mouse Model (C57bl/6 Mouse)
Roselle 📋✍⛔37450997Hibiscus-cisplatin combination treatment decreases liver toxicity in rats while increasing toxicity in lung cancer cells via oxidative stress- apoptosis pathway
Sesamin 📋✍ 38679210Sesamin ameliorates nonalcoholic hepatic steatosis by inhibiting CD36-mediated hepatocyte lipid accumulation in vitro and in vivo
Sesamol 📋 37976698Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage
Tea 📋 36196488Cumulative consumption of tea is associated with lower risk of liver cancer: updated results from the Shanghai Women's Health Study
Tomato 📋 ⛔38398886Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study
Vitamin B9 📋✍⛔37738285Folic Acid Protects against Ethanol-Induced Hepatic Mitophagy Imbalance by ROS Scavenging and Attenuating the Elevated Hcy Levels
Andrographis 📋✍⛔38467318Inhibition of hepatocellular carcinoma cell proliferation through regulation of the cell cycle, AGE RAGE, and leptin signaling pathways by a compound formulation comprised of andrographolide, wogonin, and oroxylin a derived from Andrographis Paniculata(Burm.f.) Nees
Artemisinin 📋 38409843Artesunate Inhibits Lipid Accumulation and Inflammation by Regulating the NLRP3 Inflammasome in Nonalcoholic Fatty Liver Disease
Beta-Glucan 📋✍⛔38444353β-Glucan ameliorates cisplatin-induced oxidative and histological damage in kidney and liver of rats
Betulinic Acid 📋 37423159Betulinic acid regulates tumor-associated macrophage M2 polarization and plays a role in inhibiting the liver cancer progression
Boswellic Acid 📋✍⛔37310644Acetyl-11-Keto-Beta-Boswellic Acid Has Therapeutic Benefits for NAFLD Rat Models That Were Given a High Fructose Diet by Ameliorating Hepatic Inflammation and Lipid Metabolism
Burdock 📋 ⛔37867310Arctium lappa L. root polysaccharides ameliorate CCl4-induced acute liver injury by suppressing oxidative stress, inflammation and apoptosis
Butyrate 📋 ⛔38492338Butyrate alleviates alcoholic liver disease-associated inflammation through macrophage regulation and polarization via the HDAC1/miR-155 axis
Crocetin 📋 34848360Crocetin ameliorates non-alcoholic fatty liver disease by modulating mitochondrial dysfunction in L02 cells and zebrafish model
DHEA 📋✍⛔36982376DHEA and Its Metabolites Reduce the Cytokines Involved in the Inflammatory Response and Fibrosis in Primary Biliary Cholangitis
Echinacoside 📋 38461536Echinacoside ameliorates hepatic fibrosis and tumor invasion in rats with thioacetamide-induced hepatocellular carcinoma
Ganoderic Acid 📋 38322557Ganoderic acid A attenuated hepatic impairment by down-regulating the intracellular JAK2-STAT3 signaling pathway in induced mushroom poisoning
Geraniol 📋 38362098The Inhibitory Effect of Geraniol on CCL4-induced Hepatorenal Toxicity in Pregnant Mice through the PI3K/AKT Signaling Pathway
Guava 📋 ⛔36134391Guava Leaf Extract Suppresses Fructose Mediated Non-Alcoholic Fatty Liver Disease in Growing Rats
Haritaki 📋✍⛔35351639The potential mechanism of Chebulae Fructus in the treatment of hepatocellular carcinoma on the basis of network pharmacology
Isorhamnetin 📋 37598299Isorhamnetin Exerts Antifibrotic Effects by Attenuating Platelet-Derived Growth Factor-BB-induced HSC-T6 Cells Activation via Suppressing PI3K-AKT Signaling Pathway
L-Arginine 📋✍⛔37378730Neuromodulatory role of L-arginine: nitric oxide precursor against thioacetamide-induced-hepatic encephalopathy in rats via downregulation of NF-κB-mediated apoptosis
L-Theanine 📋✍⛔38611425The Protective Effects of L-Theanine against Epigallocatechin Gallate-Induced Acute Liver Injury in Mice
Limonin 📋 37832403Limonin ameliorates cisplatin-induced acute liver injury by inhibiting 11β-hydroxysteroid dehydrogenase type 1
Phloretin 📋 37744933Metagenomic signatures reveal the key role of phloretin in amelioration of gut dysbiosis attributed to metabolic dysfunction-associated fatty liver disease by time-dependent modulation of gut microbiome
Prebiotics 📋✍⛔37834367Prebiotics and Probiotics: Therapeutic Tools for Nonalcoholic Fatty Liver Disease
Thymol 📋✍⛔37542527The anticancer effects of thymol on HepG2 cell line
Turmeric 📋✍⛔38007567Essential oil components of turmeric inhibit hepatic lipidification and liver fibrosis in a diet-induced NASH model rats
Vitexin 📋 35432812Vitexin ameliorates glycochenodeoxycholate-induced hepatocyte injury through SIRT6 and JAK2/STAT3 pathways
Aloin 📋 38038700Aloin Attenuates Oxidative Stress, Inflammation, and CCl4-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling
Alpha-Linolenic Acid 📋✍⛔38435630Alpha-Linolenic Acid Ameliorates Cognitive Impairment and Liver Damage Caused by Obesity
Beets 📋✍⛔37662597Comparing effects of beetroot juice and Mediterranean diet on liver enzymes and sonographic appearance in patients with non-alcoholic fatty liver disease: a randomized control trials
Chrysanthemum 📋✍⛔37099836Effects and mechanism of action of Chrysanthemum morifolium (Jinsi Huangju) on hyperlipidemia and non-alcoholic fatty liver disease
Cocoa 📋✍⛔37324470Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice
Cordyceps 📋✍⛔35508667Cordyceps inhibits ceramide biosynthesis and improves insulin resistance and hepatic steatosis
Cryptotanshinone 📋 37435898Cryptotanshinone ameliorates hemorrhagic shock-induced liver injury via activating the Nrf2 signaling pathway
Folate 📋✍⛔37733056Correlation of Nonalcoholic Fatty Liver Disease with Dietary Folate and Serum Folate in U.S. Adults: Cross-Sectional Analyses from National Health and Nutrition Examination Survey 2009-2018
Honey 📋✍⛔36520139Royal jelly arranges apoptotic and oxidative stress pathways and reduces damage to liver tissues of rats by down-regulation of Bcl-2, GSK3 and NF-κB and up-regulation of Caspase and Nrf-2 protein signaling pathways
Icariin 📋✍ 38621977[Study on mechanism of icariin-induced ferroptosis in HepG2 hepatoma carcinoma cells through PPARG/FABP4/GPX4 pathway]
L-Carnosine 📋✍⛔38348714Quantitative proteomics study of carnosine effect in an animal model of Western diet-induced nonalcoholic fatty liver disease
Loquat 📋✍⛔37498560Polyphenol-rich extract from loquat fruit peel prevents hyperlipidemia and hepato-nephrotoxicity in mice: in vivo study and in silico prediction of possible mechanisms involving identified polyphenols and/or their circulating metabolites
Lupeol 📋 35483487Lupeol inhibits pesticides induced hepatotoxicity via reducing oxidative stress and inflammatory markers in rats
Lutein 📋✍⛔37755751Lutein Modulates Oxidative Stress, Inflammatory and Apoptotic Biomarkers Related to Di-(2-Ethylhexyl) Phthalate (DEHP) Hepato-Nephrotoxicity in Male Rats: Role of Nuclear Factor Kappa B
Morin 📋 37802874[Morin induces autophagy and apoptosis in hepatocellular carcinoma cells through Akt/mTOR/STAT3 pathway]
MSM 📋✍⛔38099147Methylsulfonylmethane ameliorates metabolic-associated fatty liver disease by restoring autophagy flux via AMPK/mTOR/ULK1 signaling pathway
Oyster 📋 ⛔36547905Ameliorative Effects of Oyster Protein Hydrolysates on Cadmium-Induced Hepatic Injury in Mice
Pu-erh Tea 📋✍⛔34646532Protective effects of tea extracts against alcoholic fatty liver disease in mice via modulating cytochrome P450 2E1 expression and ameliorating oxidative damage
Retinoic Acid 📋 37537668ATRA sensitized the response of hepatocellular carcinoma to Sorafenib by downregulation of p21-activated kinase 1
SAMe 📋✍⛔36310362The Relationship between Prohibitin 1 Expression, Hepatotoxicity Induced by Acetaminophen, and Hepatoprotection by S-Adenosylmethionine in AML12 Cells
Scutellarin 📋 38622131Scutellarin activates IDH1 to exert antitumor effects in hepatocellular carcinoma progression
Spikenard 📋✍⛔33813393Nardostachys jatamansi Root Extract Attenuates Tumor Progression in Hepatocellular Carcinoma via Inhibition of ERK/STAT3 Pathways
Stigmasterol 📋 38678948Stigmasterol: Remodeling gut microbiota and suppressing tumor growth through Treg and CD8+ T cells in hepatocellular carcinoma
Stinging Nettle 📋✍⛔32160852Urtica dioica Extract Inhibits Cell Proliferation and Induces Apoptosis in HepG2 and HTC116 as Gastrointestinal Cancer Cell Lines
Theabrownins 📋 38642504Theabrownin from Qingzhuan tea prevents high-fat diet-induced MASLD via regulating intestinal microbiota
Theaflavins 📋✍ 37549726Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling
Vitamin K2 📋✍⛔38321064Vitamin K2 protects mice against non-alcoholic fatty liver disease induced by high-fat diet
Antioxidants 📋 ⛔36926234Antioxidant and anti-inflammatory agents in chronic liver diseases: Molecular mechanisms and therapy
Biochanin A 📋 38005330Hepatoprotective Effects of Biochanin A on Thioacetamide-Induced Liver Cirrhosis in Experimental Rats
Broccoli 📋 ⛔38458274The combination of Brassica rapa L. polysaccharides and cisplatin enhances the anti liver cancer effect and improves intestinal microbiota and metabolic disorders
Camellia 📋 ⛔36313120Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol
Carrot 📋 ⛔36225879Carotenoids in orange carrots mitigate non-alcoholic fatty liver disease progression
Catalpol 📋 37979473Catapol attenuates the aseptic inflammatory response to hepatic I/R injury in vivo and in vitro by inhibiting the HMGB1/TLR-4/NF-κB signaling pathway via the microRNA-410-3p
Cinnamon Essential Oil 📋✍⛔38034947Comparison of the virucidal efficacy of essential oils (cinnamon, clove, and thyme) against hepatitis A virus in suspension and on food-contact surfaces
Coconut Oil 📋 ⛔35293540Beneficial effects of coconut oil (Cocos nucifera) on hematobiochemicl and histopathological markers in CCL4-intoxicated rabbits
Coriander 📋 ⛔37518878Effects of Coriandrum sativum on distant organ inflammation and apoptosis due to liver ischemia/reperfusion injury
Cornus 📋 37716032Cornuside improves murine autoimmune hepatitis through inhibition of inflammatory responses
Coumaric acid 📋 37183931The protective effect of p-Coumaric acid on hepatic injury caused by particulate matter in the rat and determining the role of long noncoding RNAs MEG3 and HOTAIR
D-Mannose 📋✍⛔38293175Mannose Supplementation Curbs Liver Steatosis and Fibrosis in Murine MASH by Inhibiting Fructose Metabolism
Diallyl Trisulfide 📋 37868628Diallyl trisulfide induces pro-apoptotic autophagy via the AMPK/SIRT1 signalling pathway in human hepatocellular carcinoma HepG2 cell line
Eucalyptus 📋✍⛔35284740Cheminformatics Application in the Phytochemical and Biological Study of Eucalyptus globulus L. Bark as a Potential Hepatoprotective Drug
Flaxseed 📋✍⛔38398791Beneficial Effects of Dietary Flaxseed on Non-Alcoholic Fatty Liver Disease
Flaxseed Oil 📋✍⛔37960203Flaxseed Oil ( Linum usitatissimum) Prevents Cognitive and Motor Damage in Rats with Hyperammonemia
Ginkgetin 📋 38217097Ginkgetin exhibits antifibrotic effects by inducing hepatic stellate cell apoptosis via STAT1 activation
Ginkgolides 📋 33167504Anti-neoplastic Effect of Ginkgolide C through Modulating c-Met Phosphorylation in Hepatocellular Carcinoma Cells
Graviola 📋✍⛔38110557Effect of Ethanol Extract of Soursop ( Annona muricata L.) Stem Bark on Rat Liver Function
Honeysuckle 📋 ⛔36458288Immunomodulatory effect of polysaccharides isolated from Lonicera japonica Thunb. in cyclophosphamide-treated BALB/c mice
Isoquercitrin 📋 38069009Mixture of Peanut Skin Extract, Geniposide, and Isoquercitrin Improves the Hepatic Lipid Accumulation of Mice via Modification of Gut Microbiota Homeostasis and the TLR4 and AMPK Signaling Pathways
Lemon Balm 📋✍⛔38303002Melissa officinalis extract palliates redox imbalance and inflammation associated with hyperthyroidism-induced liver damage by regulating Nrf-2/ Keap-1 gene expression in γ-irradiated rats
Linalool 📋 ⛔37916380Hepatoprotective effects of linalool against liver ischemia-reperfusion: the role of Nrf2/HO-1/NQO1 and TLR4/RAGE/NFκB pathways
Lotus 📋 ⛔37368582Effects of Nelumbonucifera Gaertn. Petal Tea Extract on Hepatotoxicity and Oxidative Stress Induced by Mancozeb in Rat Model
Lychee 📋 ⛔35889878Litchi-Derived Polyphenol Alleviates Liver Steatosis and Gut Dysbiosis in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Double-Blinded, Placebo-Controlled Study
Oregano 📋✍⛔36284120Ameliorative effect of oregano (Origanum vulgare) versus silymarin in experimentally induced hepatic encephalopathy
Parthenolide 📋 37741815A novel SLC25A1 inhibitor, parthenolide, suppresses the growth and stemness of liver cancer stem cells with metabolic vulnerability
Pectin 📋✍⛔36615814Pectin in Metabolic Liver Disease
Proanthocyanidins 📋 37719964Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway
Protein 📋✍⛔36804020Effect of unsaturated fat and protein intake on liver fat in people at risk of unhealthy aging: 1-year results of a randomized controlled trial
Quinoa 📋 ⛔37474360High-protein compound yogurt with quinoa improved clinical features and metabolism of high-fat diet-induced nonalcoholic fatty liver disease in mice
Safranal 📋 35740022Molecular Mechanisms behind Safranal's Toxicity to HepG2 Cells from Dual Omics
Shiitake Mushrooms 📋✍⛔38257149Hepatoprotection of a Standardized Extract of Cultured Lentinula edodes Mycelia against Liver Injury Induced by Ischemia-Reperfusion and Partial Hepatectomy
Soy Protein 📋✍⛔38075211Feeding soy protein concentrates with low or high isoflavone decreases liver inflammation by reducing lipopolysaccharide translocation
Telmisartan 📋 ⛔37831115Telmisartan and candesartan promote browning of white adipose tissue and reverse fatty liver changes in high fat diet fed male albino rats
Urolithins 📋 37189743Urolithin A's Antioxidative, Anti-Inflammatory, and Antiapoptotic Activities Mitigate Doxorubicin-Induced Liver Injury in Wistar Rats
Whey Protein 📋✍⛔38573884Whey protein supplementation reduced the liver damage scores of rats fed with a high fat-high fructose diet
White Tea 📋 ⛔38628196Investigation of the effects of white tea on liver fibrosis: An experimental animal model
Apple Vinegar 📋✍⛔36564752Effect of apple vinegar on folliculogenesis and ovarian kisspeptin in a high-fat diet-induced nonalcoholic fatty liver disease in rat
Asiaticoside 📋 36169781Asiaticoside conveys an antifibrotic effect by inhibiting activation of hepatic stellate cells via the Jagged-1/Notch-1 pathway
Balloon Flower 📋✍⛔38542804Platycodi Radix Extract Prevents Hepatic Steatosis by Enhancing Bile Acid Synthesis in a High-Fat Diet-Induced Fatty Liver Mouse Model
Beta-Lapachone 📋 38092141Beta-lapachone ameliorates the progression of primary sclerosing cholangitis pathogenesis in rodent models
Bilberry 📋✍⛔31590249Anthocyanins Protect Hepatocytes against CCl 4-Induced Acute Liver Injury in Rats by Inhibiting Pro-inflammatory mediators, Polyamine Catabolism, Lipocalin-2, and Excessive Proliferation of Kupffer Cells
Bitter Melon 📋✍⛔34275705In vivo anticancer effects of Momordica charantia seed fat on hepatocellular carcinoma in a rat model
Boric Acid 📋✍⛔35940215The role of Bax/Bcl-2 and Nrf2-Keap-1 signaling pathways in mediating the protective effect of boric acid on acrylamide-induced acute liver injury in rats
Caffeic Acid 📋✍⛔38102533The Hepatorenal Protective Potential of Caffeic Acid Consumption on the Arsenic-Exposed Syrian Mice
Cardamom 📋✍⛔37318456Protective effect of ethanolic extract of Elettaria Cardamomum against gentamicin hepato-renal toxicity in male albino rats
Cherry 📋 ⛔37266135Phytochemical screening of Prunus avium for its antioxidative and anti-mutagenic potential against DMBA-induced hepatocarcinogenesis
Choline 📋✍⛔38172213Choline supplementation mitigates effects of bilirubin in cerebellar granule neurons in vitro
Citicoline 📋✍⛔37291355Valuable effects of lactobacillus and citicoline on steatohepatitis: role of Nrf2/HO-1 and gut microbiota
Citral 📋 38132361Citral-Enriched Fraction of Lemon Essential Oil Mitigates LPS-Induced Hepatocyte Injuries
Costus 📋✍⛔37396159Costunolide alleviated DDC induced ductular reaction and inflammatory response in murine model of cholestatic liver disease
Diallyl Disulfide 📋 36559076Diallyl Disulfide Induces Chemosensitization to Sorafenib, Autophagy, and Cell Cycle Arrest and Inhibits Invasion in Hepatocellular Carcinoma
Diallyl Sulfide 📋 37209385Autophagy blockage and lysosomal dysfunction are involved in diallyl sulfide-induced inhibition of malignant growth in hepatocellular carcinoma cells
Diosmetin 📋 34755740Diosmetin inhibits cell growth and proliferation by regulating the cell cycle and lipid metabolism pathway in hepatocellular carcinoma
Eleuthero 📋✍⛔37467688Syringin alleviates hepatic fibrosis by enhancing autophagic flux and attenuating ER stress-TRIB3/SMAD3 in diabetic mice
Fennel 📋✍⛔36552526Phenolics and Volatile Compounds of Fennel ( Foeniculum vulgare) Seeds and Their Sprouts Prevent Oxidative DNA Damage and Ameliorates CCl4-Induced Hepatotoxicity and Oxidative Stress in Rats
Galangal 📋✍⛔37757646Hepatoprotective effects of Alpinia officinarum rhizome extract on cisplatin-induced hepatotoxicity in rats: A biochemical, histopathological and immunohistochemical study
L-Citrulline 📋✍⛔34532001L-citrulline inhibits body weight gain and hepatic fat accumulation by improving lipid metabolism in a rat nonalcoholic fatty liver disease model
L-Glutamine 📋✍⛔38459503Glutamine prevents high-fat diet-induced hepatic lipid accumulation in mice by modulating lipolysis and oxidative stress
Linoleic Acid 📋✍⛔35958259Dietary linoleic acid and the ratio of unsaturated to saturated fatty acids are inversely associated with significant liver fibrosis risk: A nationwide survey
Liquiritigenin 📋 37455324Liquiritigenin regulates insulin sensitivity and ameliorates inflammatory responses in the nonalcoholic fatty liver by activation PI3K/AKT pathway
Magnolol 📋 38402928The natural compounds, Magnolol or Honokiol, promote adipose tissue browning and resist obesity through modulating PPARα/γ activity
Malvidin 📋 36063870Malvidin protects against lipopolysaccharide-induced acute liver injury in mice via regulating Nrf2 and NLRP3 pathways and suppressing apoptosis and autophagy
Milk 📋 ⛔37853817Yak milk protects against alcohol-induced liver injury in rats
Morusin 📋 34638959Antitumor Effect of Morusin via G1 Arrest and Antiglycolysis by AMPK Activation in Hepatocellular Cancer
Nicotinamide 📋✍⛔38087034Hepatoprotective Effect of Nicotinamide Versus Lead-Motivated Hepatotoxicity in Rats via Correcting Effect on Nuclear Factor-kβ Pathway and Glutathione Metabolism
Nuciferine 📋 36106619Nuciferine Protects Against High-Fat Diet-Induced Hepatic Steatosis via Modulation of Gut Microbiota and Bile Acid Metabolism in Rats
Olive Polyphenols 📋 34671630The Extra Virgin Olive Oil Polyphenol Oleocanthal Exerts Antifibrotic Effects in the Liver
Omega-6 Fatty Acids 📋✍⛔35648467Associations of serum n-3 and n-6 polyunsaturated fatty acids with prevalence and incidence of non-alcoholic fatty liver disease
Onion 📋✍⛔35377371Protective role of Siberian onions against toxin-induced liver dysfunction: an insight into health-promoting effects
Osmanthus 📋✍⛔37852338Nuezhenoside G13 from Osmanthus fragrans fruit ameliorates Concanavalin A-induced autoimmune hepatitis by regulating the NF-κB/MAPK pathway
Paeonol 📋 38574779Paeonol attenuates nonalcoholic steatohepatitis by regulating intestinal flora and AhR/NLRP3/Caspase-1 metabolic pathway
Papaya 📋✍⛔36396758Prophylactic and curative effects of Carica papaya Linn. pulp extract against carbon tetrachloride-induced hepatotoxicity in male rats
Patchouli 📋✍⛔34899351Network Pharmacology-Based Analysis of Pogostemon cablin (Blanco) Benth Beneficial Effects to Alleviate Nonalcoholic Fatty Liver Disease in Mice
Peppermint Essential Oil 📋✍⛔30961427Synergistic effects of deuterium depleted water and Mentha longifolia L. essential oils on sepsis-induced liver injuries through regulation of cyclooxygenase-2
Persimmon 📋 ⛔35766964Persimmon Water Extract Suppresses Hepatic Lipotoxicity by Regulating Lipid Metabolites
Phosphatidylcholine 📋✍⛔38262589Oral supplementation of phosphatidylcholine attenuates the onset of a diet-induced metabolic dysfunction-associated steatohepatitis in female C57BL/6J mice
Piperlongumine 📋 36227332Piperlongumine and bortezomib synergically inhibit cholangiocarcinoma via ER stress-induced cell death
PQQ 📋✍⛔34997497Pyrroloquinoline quinone ameliorates liver injury in mice induced by cyclophosphamide
Procyanidins 📋 ⛔35565726Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARγ-Dependent Mechanism
Quercitrin 📋 34025394Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity
Red Yeast Rice 📋✍⛔37358849Association of Statin Use With Risk of Liver Disease, Hepatocellular Carcinoma, and Liver-Related Mortality
Rice 📋 ⛔36615905Red Rice Bran Extract Alleviates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease and Dyslipidemia in Mice
Rosemary 📋✍⛔33804618Evaluation of Hepatoprotective Activity and Oxidative Stress Reduction of Rosmarinus officinalis L. Shoots Tincture in Rats with Experimentally Induced Hepatotoxicity
Soy Isoflavones 📋✍⛔37375574The Role of Choline, Soy Isoflavones, and Probiotics as Adjuvant Treatments in the Prevention and Management of NAFLD in Postmenopausal Women
Tribulus Terrestris 📋✍⛔37416661Promoting liver cancer cell apoptosis effect of Tribulus terrestris L. via reducing sphingosine level was confirmed by network pharmacology with metabolomics
Vitamin B1 📋✍⛔37720374Association of vitamin B1 with cardiovascular diseases, all-cause and cardiovascular mortality in US adults
Vitamin B12 📋✍⛔37312722Hepatoprotective Effect of Vitamin B12 in Acetaminophen Induce Hepatotoxicity in Male Rats
Vitamins 📋 37608217Association between use of vitamin and mineral supplement and non-alcoholic fatty liver disease in hypertensive adults
Yogurt 📋 ⛔38628190Probiotic yogurt regulates gut microbiota homeostasis and alleviates hepatic steatosis and liver injury induced by high-fat diet in golden hamsters
Aloe-Emodin 📋 37900162Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments
Anethole 📋 34453252Amelioration of oxidative stress by trans-Anethole via modulating phase I and phase II enzymes against hepatic damage induced by CCl 4 in male Wistar rats
Apricot Kernels 📋✍⛔34146630Phytochemical characterization and biological activity of apricot kernels' extract in yeast-cell based tests and hepatocellular and colorectal carcinoma cell lines
Arjuna 📋✍⛔37665010Systematic elucidation of the multi-target pharmacological mechanism of Terminalia arjuna against congestive cardiac failure via network pharmacology and molecular modelling approaches
Ashitaba 📋✍⛔37920601Exploring the underlying mechanisms of Ashitaba in the management of non-alcoholic fatty liver disease by integrating the analysis of transcriptomics and metabolomics
Avocado Oil 📋 ⛔36601051Avocado oil alleviates non-alcoholic fatty liver disease by improving mitochondrial function, oxidative stress and inflammation in rats fed a high fat-High fructose diet
Basil Essential Oil 📋✍⛔35126122Ocimum basilicum Essential Oil Modulates Hematotoxicity, Oxidative Stress, DNA Damage, and Cell Cycle Arrest Induced by β-cyfluthrin in Rat Liver
Bitter Orange 📋✍⛔35894798Optimization of the extract from flower of Citrus aurantium L. var. amara Engl. and its inhibition of lipid accumulation
Blackberry 📋 ⛔33719965Anti-Proliferative and Anti-Telomerase Effects of Blackberry Juice and Berry-Derived Polyphenols on HepG2 Liver Cancer Cells and Normal Human Blood Mononuclear Cells
Chaga Mushrooms 📋✍⛔35601068Inonotsuoxide B suppresses hepatic stellate cell activation and proliferation via the PI3K/AKT and ERK1/2 pathway
Chicory 📋✍⛔37895942Modulation of Hepatic Functions by Chicory ( Cichorium intybus L.) Extract: Preclinical Study in Rats
Coconut 📋 ⛔34652342Tender Coconut Water Protects Mice From Ischemia-Reperfusion-Mediated Liver Injury and Secondary Lung Injury
Cyanidin 📋✍ 36552590Cyanidin Alleviated CCl4-Induced Acute Liver Injury by Regulating the Nrf2 and NF-κB Signaling Pathways
Dairy 📋 37244850Dairy product consumption and risk of non-alcoholic fatty liver disease: A systematic review and meta-analysis of observational studies
DIM 📋✍⛔36232707Hepatoprotective Effects of a Natural Flavanol 3,3'-Diindolylmethane against CCl4-Induced Chronic Liver Injury in Mice and TGFβ1-Induced EMT in Mouse Hepatocytes via Activation of Nrf2 Cascade
Dioscin 📋 33836263Dioscin ameliorates methotrexate-induced liver and kidney damages via adjusting miRNA-145-5p-mediated oxidative stress
Eucommia 📋✍⛔38611393Polysaccharides from Eucommia ulmoides Oliv. Leaves Alleviate Acute Alcoholic Liver Injury by Modulating the Microbiota-Gut-Liver Axis in Mice
Fiber 📋✍⛔38730369Exploring the association between dietary fiber intake and hepatic steatosis: insights from NHANES
Fish 📋 ⛔35973188A freshwater fish-based diet alleviates liver steatosis by modulating gut microbiota and metabolites: a clinical randomized controlled trial in Chinese patients with nonalcoholic fatty liver disease
Genipin 📋 37354317Genipin protects against acute liver injury by abrogating ferroptosis via modification of GPX4 and ALOX15-launched lipid peroxidation in mice
Grapefruit Essential Oil 📋✍⛔32760938Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis
Haskap 📋 37764808Lonicera Caerulea Juice Alleviates Alcoholic Liver Disease by Regulating Intestinal Flora and the FXR-FGF15 Signaling Pathway
HMB 📋✍⛔34371806The Effects of 12-Week Beta-Hydroxy-Beta-Methylbutyrate Supplementation in Patients with Liver Cirrhosis: Results from a Randomized Controlled Single-Blind Pilot Study
Jujube 📋 ⛔36606101Hepatoprotective Effect of Dried Red Jujube Fruit Extract Against Acetaminophen-Induced Acute Hepatotoxicity
Kombucha 📋✍⛔36095960Kombucha tea improves glucose tolerance and reduces hepatic steatosis in obese mice
Krill Oil 📋✍⛔35613674Antarctic Krill Oil ameliorates liver injury in rats exposed to alcohol by regulating bile acids metabolism and gut microbiota
L-Methionine 📋✍⛔38367245l-Methionine potentiates anticancer activity of Sorafenib by epigenetically altering DUSP3/ERK pathway in hepatocellular carcinoma
L-Tryptophan 📋✍⛔38152280Tryptophan Prevents the Development of Non-Alcoholic Fatty Liver Disease
Lauric Acid 📋✍ 38166588Lauric acid attenuates hepato-metabolic complications and molecular alterations in high-fat diet-induced Non-alcoholic Fatty Liver Disease in rats
Mango Leaf 📋 ⛔35909999Evaluating the hepatoprotective, ameliorative and antioxidant potentials of the crude aqueous leafy extracts of Mangifera indica plant against acute paracetamol-induced hepatotoxicity in a mouse model
Marjoram 📋 ⛔34035827Antioxidant and Anti-Inflammatory Effects of Origanum majorana L. Methanolic Extract on Bile Duct Ligation in Male Rats
Mucuna Pruriens 📋✍⛔34789221Ethanolic extract of Mucuna pruriens leaves ameliorates carbon tetrachloride and rifampicin-induced hepatotoxicity and nephrotoxicity in wistar albino rat
NAD 📋 35983933Nicotinamide adenine dinucleotide attenuates acetaminophen-induced acute liver injury via activation of PARP1, Sirt1, and Nrf2 in mice
Neem 📋✍ 38243572Antioxidant and Chemopreventive Effects of Azadirachta indica on Lead Acetate-induced Hepatotoxicity in Male Wistar Rats
Nimbolide 📋 35229912Nimbolide attenuates gut dysbiosis and prevents bacterial translocation by improving intestinal barrier integrity and ameliorating inflammation in hepatocellular carcinoma
Noni 📋 ⛔36516056Morinda citrifolia Extract Prevents Alcoholic Fatty Liver Disease by Improving Gut Health
Nootkatone 📋 37755794Nootkatone Mitigated Melamine-Evoked Hepatotoxicity by Featuring Oxidative Stress and Inflammation Interconnected Mechanisms: In Vivo and In Silico Approaches
Nutmeg 📋✍⛔35565666Myristica fragrans Extract Regulates Gut Microbes and Metabolites to Attenuate Hepatic Inflammation and Lipid Metabolism Disorders via the AhR-FAS and NF-κB Signaling Pathways in Mice with Non-Alcoholic Fatty Liver Disease
Oleic Acid 📋 ⛔37253404Oleic acid improves hepatic lipotoxicity injury by alleviating autophagy dysfunction
Oolong Tea 📋 ⛔34646532Protective effects of tea extracts against alcoholic fatty liver disease in mice via modulating cytochrome P450 2E1 expression and ameliorating oxidative damage
Orange 📋 ⛔31049130The Preventive Effects and the Mechanisms of Action of Navel Orange Peel Hydroethanolic Extract, Naringin, and Naringenin in N-Acetyl-p-aminophenol-Induced Liver Injury in Wistar Rats
Pistachio 📋✍⛔31599067Mastiha (Pistacia lentiscus) Improves Gut Microbiota Diversity, Hepatic Steatosis, and Disease Activity in a Biopsy-Confirmed Mouse Model of Advanced Non-Alcoholic Steatohepatitis and Fibrosis
Prunella Vulgaris 📋✍⛔38040415Exploring the mechanism of bioactive components of Prunella vulgaris L. in treating hepatocellular carcinoma based on network pharmacology
PUFA 📋 35958253Dietary fatty acids and risk of non-alcoholic steatohepatitis: A national study in the United States
Rapeseed Oil 📋✍ 36691598Effects of Different Vegetable Oils on the Nonalcoholic Fatty Liver Disease in C57/BL Mice
Rhubarb 📋 ⛔38349666Integration of pharmacodynamics and metabolomics to reveal rhubarb anthraquinone protection against nonalcoholic fatty liver disease rat model
Rosemary Essential Oil 📋✍⛔36558044The Synergistic Hepatoprotective Activity of Rosemary Essential Oil and Curcumin: The Role of the MEK/ERK Pathway
Sesame Oil 📋 ⛔36707815Supplementation with sesame oil suppresses genotoxicity, hepatotoxicity and enterotoxicity induced by sodium arsenite in rats
Soy 📋✍⛔35015019Preventive effects of black soybean polyphenols on non-alcoholic fatty liver disease in three different mouse models
Spermidine 📋 36892418Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S
St. Johns Wort 📋✍⛔37375834Hypericum perforatum L. and the Underlying Molecular Mechanisms for Its Choleretic, Cholagogue, and Regenerative Properties
Star Fuit 📋 ⛔31704616Extract of Averrhoacarambola L. (Oxalidaceae) roots ameliorates carbon tetrachloride-induced hepatic fibrosis in rats
Tamarind 📋 ⛔36900595Antialcohol and Hepatoprotective Effects of Tamarind Shell Extract on Ethanol-Induced Damage to HepG2 Cells and Animal Models
Tannic Acid 📋✍⛔38393487Cyto and Genoprotective Potential of Tannic Acid Against Cadmium and Nickel Co-exposure Induced Hepato-Renal Toxicity in BALB/c Mice
Thyme 📋✍⛔37628072Thyme ( Thymus quinquecostatus Celak) Polyphenol-Rich Extract (TPE) Alleviates HFD-Induced Liver Injury in Mice by Inactivating the TLR4/NF-κB Signaling Pathway through the Gut-Liver Axis
Trehalose 📋 ⛔37581638Trehalose-induced SIRT1/AMPK activation regulates SREBP-1c/PPAR-α to alleviate lipid accumulation in aged liver
Wormwood Essential Oil 📋 ⛔37347548Hepatoprotective effect of Artemisia Argyi essential oil on bisphenol A-induced hepatotoxicity via inhibition of ferroptosis in mice
Almond 📋 ⛔34057922Almond protects the liver in coronary artery disease: A randomized controlled clinical trial
Anise 📋✍⛔28465696Pimpinella anisum L. fruit: Chemical composition and effect on rat model of nonalcoholic fatty liver disease
Arctiin 📋 38205087Role of Arctiin in Fibrosis and Apoptosis in Experimentally Induced Hepatocellular Carcinoma in Rats
Asparagus 📋 ⛔34335854HIF-1 α RNAi Combined with Asparagus Polysaccharide Exerts an Antiangiogenesis Effect on Hepatocellular Carcinoma In Vitro and In Vivo
Banana 📋 ⛔35018684Banana green peels extract protects against nonalcoholic fatty liver disease in high-fat-fed mice through modulation of lipid metabolism and inflammation
Barley 📋✍⛔36495148Barley Grass Juice Attenuates Hydrodynamic Transfection-Induced HCC Initiation in Mice
Basil 📋✍⛔33603821Toxicological Evaluation and Hepatoprotective Efficacy of Rosmarinic Acid-Rich Extract from Ocimum basilicum L
Bee Pollen 📋✍⛔34344946Potential therapeutic effect of thymoquinone and/or bee pollen on fluvastatin-induced hepatitis in rats
Beta-Alanine 📋✍⛔37251265Ellagic acid from whole pomegranate fruit reduces liver injury in a rat model of hepatic cholestasis
Bile Salts 📋 29104811Bile acid metabolism and signaling in liver disease and therapy
Bilobalide 📋 38125341Bilobalide attenuates lipopolysaccharide‑induced HepG2 cell injury by inhibiting TLR4‑NF‑κB signaling via the PI3K/Akt pathway
Black Tea Polyphenols 📋 25927469Protective effect of theaflavin-enriched black tea extracts against dimethylnitrosamine-induced liver fibrosis in rats
Buckwheat 📋 ⛔36149348The important role of glycerophospholipid metabolism in the protective effects of polyphenol-enriched Tartary buckwheat extract against alcoholic liver disease
Calcium 📋✍⛔33838230Calcium supplementation relieves high-fat diet-induced liver steatosis by reducing energy metabolism and promoting lipolysis
Capsanthin 📋 34161164Protective Role of Dietary Capsanthin in a Mouse Model of Nonalcoholic Fatty Liver Disease
Cardamonin 📋 33043385Cardamonin inhibits cell proliferation by caspase-mediated cleavage of Raptor
Carnosol 📋 37073668Carnosol Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells in vitro by Regulating the AMPK Signaling Pathway
Chamomile 📋✍⛔32509999Hepatoprotective effect of Matricaria chamomilla aqueous extract against 1,2-Dimethylhydrazine-induced carcinogenic hepatic damage in mice
Chia Seeds 📋 ⛔35322435Chia seeds and chemical-elicited sprouts supplementation ameliorates insulin resistance, dyslipidemia, and hepatic steatosis in obese rats
Chondroitin 📋✍⛔35667460Chondroitin sulfate stimulates the secretion of H 2 S by Desulfovibrio to improve insulin sensitivity in NAFLD mice
Citrus Fruits 📋 ⛔35493423Sinensetin suppresses angiogenesis in liver cancer by targeting the VEGF/VEGFR2/AKT signaling pathway
Conjugated Linoleic Acid 📋✍⛔36132168Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells
Coriander Essential Oil 📋✍⛔30932786Hepatoprotective Activity of Linalool in Rats Against Liver Injury Induced by Carbon Tetrachloride
Delphinidin 📋 36179123Delphinidin induces autophagic flux blockage and apoptosis by inhibiting both multidrug resistance gene 1 and DEAD-box helicase 17 expressions in liver cancer cells
Fruits 📋 37101636Therapeutic potential of bioactive phytoconstituents found in fruits in the treatment of non-alcoholic fatty liver disease: A comprehensive review
Garlic Oil 📋 ⛔37964042Allium sativum Essential Oil Supplementation Reverses the Hepatic Inflammation, Genotoxicity and Apoptotic Effects in Swiss Albino Mice Intoxicated with the Lead Nitrate
Giloy 📋✍⛔38280221Traditional uses, hepatoprotective potential, and phytopharmacology of Tinospora cordifolia: a narrative review
Ginger Essential Oil 📋✍ 26900108Ginger Essential Oil Ameliorates Hepatic Injury and Lipid Accumulation in High Fat Diet-Induced Nonalcoholic Fatty Liver Disease
Ginkgolic Acid 📋 38387271Ginkgolic acid inhibits the expression of SAE1 and induces ferroptosis to exert an anti-hepatic fibrosis effect
Glucosamine 📋✍⛔38420347Glucosamine attenuates alcohol-induced acute liver injury via inhibiting oxidative stress and inflammation
Glutathione 📋✍⛔36548773Epigallocatechin Gallate and Glutathione Attenuate Aflatoxin B1-Induced Acute Liver Injury in Ducklings via Mitochondria-Mediated Apoptosis and the Nrf2 Signalling Pathway
Grape Seed Oil 📋 ⛔38278024The black Vitis vinifera seed oil saponifiable fraction ameliorates hepatocellular carcinoma in vitro and in vivo via modulating apoptosis and ROS/NF-κB signaling
Grapefruit extract 📋✍⛔35043844Explore the antiproliferative phytocompounds from ethanolic extracts of Citrus paradisi against liver cancer cell line by chemical analysis using TLC and FT-IR spectroscopy
Hazelnut 📋 ⛔31540081Dietary Supplementation with Hazelnut Oil Reduces Serum Hyperlipidemia and Ameliorates the Progression of Nonalcoholic Fatty Liver Disease in Hamsters Fed a High-Cholesterol Diet
Holy Basil 📋✍⛔37860117Hepatoprotective effects of bioactive compounds from traditional herb Tulsi ( Ocimum sanctum Linn) against galactosamine-induced hepatotoxicity in rats
Indian Barberry 📋✍⛔31888241Berberis aristata, Elaeis guineensis and Coffea canephora Extracts Modulate the Insulin Receptor Expression and Improve Hepatic Steatosis in NAFLD Patients: A Pilot Clinical Trial
Jasmine 📋 ⛔33957828The role of active metabolites isolated from Jasminum multiflorum flowers against hepatitis C virus infection and related hepatocellular carcinoma
L-Alanine 📋✍⛔35698613Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis
L-Leucine 📋✍⛔35245436Amelioration of hepatic steatosis by dietary essential amino acid-induced ubiquitination
L-Lysine 📋✍⛔37648521L-lysine supplementation attenuates experimental autoimmune hepatitis in a chronic murine model
Laminaria 📋✍⛔36355026Laminaria japonica Peptides Suppress Liver Cancer by Inducing Apoptosis: Possible Signaling Pathways and Mechanism
Lavender 📋✍⛔35446915Cytotoxic effects of Lavandula angustifolia seed extracts on the viability of Huh-7 and Chang liver cells
Lemon 📋 ⛔38204757Citrus limon (L.) Osbeck Fruit Peel Extract Attenuates Carbon Tetrachloride-Induced Hepatocarcinogenesis in Sprague-Dawley Rats
Lemon Essential Oil 📋✍⛔38132361Citral-Enriched Fraction of Lemon Essential Oil Mitigates LPS-Induced Hepatocyte Injuries
Lemongrass 📋✍⛔33051984Citronellal ameliorates doxorubicin-induced hepatotoxicity via antioxidative stress, antiapoptosis, and proangiogenesis in rats
Ligustilide 📋 38157696Targeting RXFP1 by Ligustilide: A novel therapeutic approach for alcoholic hepatic steatosis
Lime 📋 ⛔37049726Metabolomic Analysis of Phytochemical Compounds from Ethanolic Extract of Lime ( Citrus aurantifolia) Peel and Its Anti-Cancer Effects against Human Hepatocellular Carcinoma Cells
Liquiritin 📋 36008890Liquiritin alleviates alpha-naphthylisothiocyanate-induced intrahepatic cholestasis through the Sirt1/FXR/Nrf2 pathway
Maca Root 📋✍⛔36296947Antioxidative and Energy Metabolism-Improving Effects of Maca Polysaccharide on Cyclophosphamide-Induced Hepatotoxicity Mice via Metabolomic Analysis and Keap1-Nrf2 Pathway
Modified Citrus Pectin 📋✍⛔27010252Modified citrus pectin stops progression of liver fibrosis by inhibiting galectin-3 and inducing apoptosis of stellate cells
Mushrooms 📋 ⛔38154526Ganoderma lucidum ethanol extracts ameliorate hepatic fibrosis and promote the communication between metabolites and gut microbiota g_Ruminococcus through the NF-κB and TGF-β1/Smads pathways
Myrtle 📋✍⛔32333355Myrtle (Myrtus communis) leaf extract suppresses hepatotoxicity induced by monosodium glutamate and acrylamide through obstructing apoptosis, DNA fragmentation, and cell cycle arrest
Neferine 📋 37031639Neferine ameliorates nonalcoholic steatohepatitis through regulating AMPK pathway
Okra 📋 ⛔36481254A pectic polysaccharide from fresh okra (Abelmoschus esculentus L.) beneficially ameliorates CCl4-induced acute liver injury in mice by antioxidation, inhibition of inflammation and modulation of gut microbiota
Orange Essential Oil 📋✍⛔35005749Protective effect of orange essential oil on the formation of non-alcoholic fatty liver disease caused by high-fat diet
Oregano Essential Oil 📋✍⛔38613208Therapeutic benefit of oregano oil in the acute idiosyncratic hepatotoxicity induced by carbon tetrachloride in rats: Adverse effects of high dose of oreganum
Parsley 📋 ⛔36379859Hepatoprotective effects of parsley (Petroselinum Crispum) extract in rats with bile duct ligation
Peach 📋 ⛔36105786Peach Kernel Extracts Inhibit Lipopolysaccharide-Induced Activation of HSC-T6 Hepatic Stellate Cells
Perilla 📋✍ 36541423Perillartine protects against metabolic associated fatty liver in high-fat diet-induced obese mice
Pineapple 📋✍⛔25699088Antioxidant effects of pineapple vinegar in reversing of paracetamol-induced liver damage in mice
Plum 📋 ⛔28638096Identification of a Flavonoid Isolated From Plum (Prunus Domestica) as a Potent Inhibitor of Hepatitis C Virus Entry
Pomelo 📋 ⛔37419271Aqueous extract of pummelo pulp (Citrus maxima) improves the biochemical profile and reduces the inflammation process in Wistar rats with non-alcoholic fatty liver disease
Psyllium 📋✍⛔35920178The different effects of psyllium husk and orlistat on weight control, the amelioration of hypercholesterolemia and non-alcohol fatty liver disease in obese mice induced by a high-fat diet
Radish 📋 ⛔36501112Hepatoprotective Effects of Radish ( Raphanus sativus L.) on Acetaminophen-Induced Liver Damage via Inhibiting Oxidative Stress and Apoptosis
Rhodiola 📋✍⛔37457904Effect of Rhodiola rosea Rhizome and Punica granatum Fruit Peel on the Metabolic Processes and Physiological Activity of Rats Fed with Excessively Fat Diet
Rosavin 📋 ⛔36077546Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death
Safflower 📋✍⛔26290634Protective effect of Salvia miltiorrhiza and Carthamus tinctorius extract against lipopolysaccharide-induced liver injury
Sage Essential Oil 📋 ⛔33106906Anti-oxidant and hepatoprotective effects of Salvia officinalis essential oil against vanadium-induced oxidative stress and histological changes in the rat liver
Scutellarein 📋 37232353Scutellarein regulates the PTEN/AKT/NFκB signaling pathway to reduce pirarubicin related liver inflammation
Sea Cucumber 📋 38540953Sea Cucumber Polysaccharide from Stichopus japonicu and Its Photocatalytic Degradation Product Alleviate Acute Alcoholic Liver Injury in Mice
Seaweeds 📋 ⛔36981236Antioxidant Activity and Inhibition of Liver Cancer Cells' Growth of Extracts from 14 Marine Macroalgae Species of the Mediterranean Sea
Sesamolin 📋 36430326Sesamolin Alleviates Nonalcoholic Fatty Liver Disease through Modulating Gut Microbiota and Metabolites in High-Fat and High-Fructose Diet-Fed Mice
Shilajit 📋✍⛔35258780Protective Roles of Shilajit in Modulating Resistin, Adiponectin, and Cytokines in Rats with Non-alcoholic Fatty Liver Disease
Sirtuin Activators 📋 38034869Sirtuin 1 alleviates alcoholic liver disease by inhibiting HMGB1 acetylation and translocation
Soybean Oil 📋 ⛔35276916A Lard and Soybean Oil Mixture Alleviates Low-Fat-High-Carbohydrate Diet-Induced Nonalcoholic Fatty Liver Disease in Mice
Strawberry 📋✍⛔36901426Strawberry, Blueberry, and Strawberry-Blueberry Blend Beverages Prevent Hepatic Steatosis in Obese Rats by Modulating Key Genes Involved in Lipid Metabolism
Sweet Potato 📋 ⛔36505243Sweet potato extract alleviates high-fat-diet-induced obesity in C57BL/6J mice, but not by inhibiting pancreatic lipases
Syringic Acid 📋 35543257Syringic acid and silymarin concurrent administration inhibits sodium valproate-induced liver injury in rats
Tea Polyphenols 📋 36370998ROS/ER stress contributes to trimethyltin chloride-mediated hepatotoxicity; Tea polyphenols alleviate apoptosis and immunosuppression
Tetrahydrocurcumin 📋✍ 18395899Anti-cancer and Anti-Angiogenic Effects of Curcumin and Tetrahydrocurcumin on Implanted Hepatocellular Carcinoma in Nude Mice
Valerian Root 📋✍⛔33024815Valeric Acid Suppresses Liver Cancer Development by Acting as a Novel HDAC Inhibitor
Vitamin B3 📋✍⛔37836412Association between Dietary Niacin Intake and Nonalcoholic Fatty Liver Disease: NHANES 2003-2018
Vitamin B6 📋✍⛔34370653Antihyperlipidemic and Hepatoprotective Properties of Vitamin B6 Supplementation in Rats with High-Fat Diet-Induced Hyperlipidemia
Vitamin B8 📋✍⛔36963888Clinical effectiveness of α-lipoic acid, myo-inositol and propolis supplementation on metabolic profiles and liver function in obese patients with NAFLD: A randomized controlled clinical trial
Vitamin K2 mk-4 📋✍ 21410069Effect of Vitamin K2 on the Development of Hepatocellular Carcinoma in Type C Cirrhosis
White Mushrooms 📋 ⛔34451856In Vitro Antiviral Activity of Tyrosinase from Mushroom Agaricus bisporus against Hepatitis C Virus
Wine 📋 ⛔37712265[Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis]
Withanolides 📋 38301983Withanolides from the active extract of Physalis angulate and their anti-hepatic fibrosis effects
Yam 📋 34522634Therapeutic efficacy of a Dioscorea membranacea extract in a rat model of hepatocellular carcinoma: Histopathological aspects
Yohimbine 📋✍ 37952411Yohimbine ameliorates liver inflammation and fibrosis by regulating oxidative stress and Wnt/β-catenin pathway
Zeaxanthin 📋✍⛔36690321Zeaxanthin prevents ferroptosis by promoting mitochondrial function and inhibiting the p53 pathway in free fatty acid-induced HepG2 cells
Alpha GPC 📋✍⛔27861548Targeting Mitochondrial Dysfunction with L-Alpha Glycerylphosphorylcholine
Argan Oil 📋✍⛔32683986Protective effect of Argan oil on mitochondrial function and oxidative stress against acrylamide-induced liver and kidney injury in rats
Asafoetida 📋✍⛔31262162Evaluating the role of dithiolane rich fraction of Ferula asafoetida (apiaceae) for its antiproliferative and apoptotic properties: in vitro studies
Astragalin 📋 28654261Astragalin Reduces Hexokinase 2 through Increasing miR-125b to Inhibit the Proliferation of Hepatocellular Carcinoma Cells in Vitro and in Vivo
Avocado 📋✍⛔35122196Protective effects of Persea americana fruit and seed extracts against chemically induced liver cancer in rats by enhancing their antioxidant, anti-inflammatory, and apoptotic activities
Bay Leaf 📋 ⛔35546977Biological Effects of Aqueous Extract of Laurus noboilis L. Leaves on Some Histological and Immunological Parameters in Male Rat Liver Affected by Aluminum Chloride
Berries 📋 35791473Effect of Rubus extract on TLR4/NF-kappa B signaling pathway in alcoholic liver fibrosis rats
Cabbage 📋 ⛔34974788Cabbage juice protect against lead-induced liver and kidney damage in male Wistar rat
Calcium D-Glucarate 📋✍⛔36771439Mechanistic Understanding of D-Glucaric Acid to Support Liver Detoxification Essential to Muscle Health Using a Computational Systems Biology Approach
Camphor 📋✍⛔35866389Camphor Seed Kernel Oil Beneficial Effects the Gut Microbiota of the Non-Alcoholic Fatty Liver Disease Mice
Caraway Essential Oil 📋 ⛔20608729Antioxidant and hepatoprotective potential of essential oils of coriander (Coriandrum sativum L.) and caraway (Carum carvi L.) (Apiaceae)
Cashew 📋 ⛔38298047Antagonistic effectiveness of Anacardium occidentale leaf extract on lead-acetate exposure-induced hepatorenal toxicity in rats
Celery 📋 ⛔38516746Ameliorating Effect of Apium graveolens (Celery) Extracts on IL-6 Plasma Level and Expression of Caspase 3 on Liver in Animal Model of Lead Intoxication
Chicoric Acid 📋 32654534Fish oil and chicoric acid combination protects better against palmitate-induced lipid accumulation via regulating AMPK-mediated SREBP-1/FAS and PPARα/UCP2 pathways
Chitosan 📋✍⛔37749921Pharmacodynamic study of chitosan in combination with salvianolic acid B in the treatment of CC14 -induced liver fibrosis in mice
Cinnamaldehyde 📋 33923441Protective Effects of Cinnamaldehyde on the Inflammatory Response, Oxidative Stress, and Apoptosis in Liver of Salmonella typhimurium-Challenged Mice
Clove 📋 ⛔36660448Protective Effect of Hydroalcoholic Extract of Clove on Thioacetamide-Induced Hepatotoxicity Animal Model: Effects Hydroalcoholic Extract of Clove Against Hepatotoxicity
Clove Essential Oil 📋 ⛔38034947Comparison of the virucidal efficacy of essential oils (cinnamon, clove, and thyme) against hepatitis A virus in suspension and on food-contact surfaces
Corn 📋 ⛔35537139Corn peptides improved obesity-induced non-alcoholic fatty liver disease through relieving lipid metabolism, insulin resistance and oxidative stress
Corn Silk 📋✍⛔33824122Antioxidant characteristics and hepatoprotective effects of a formula derived from Maydis stigma, Nelumbo nucifera and Taraxacum officinale against carbon tetrachloride-induced hepatic damage in rats
Creatine 📋✍⛔33374297Creatine Alleviates Doxorubicin-Induced Liver Damage by Inhibiting Liver Fibrosis, Inflammation, Oxidative Stress, and Cellular Senescence
Cumin 📋 ⛔34328087Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats
Dill 📋 ⛔34704009Favorable effects of Anethum graveolens on liver oxidative stress and cholesterol 7 alpha-hydroxylase levels in non-alcoholic fatty liver disease (NAFLD) rat models
DMAE 📋✍⛔1646761Improvement of estradiol 17 beta-D-glucuronide cholestasis by intravenous administration of dimethylethanolamine in the rat
Elderberry 📋✍⛔30082013[Protective effect of Sambucus willamsii hance fruit oil on acute liver injury in mice]
Equol 📋✍⛔37565591Association between equol and non-alcoholic fatty liver disease in Japanese women in their 50s and 60s
Essential Oils 📋 ⛔33072411Hepatoprotective Essential Oils: A Review
Eurycomanone 📋 19508737Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53
Evening Primrose Oil 📋✍⛔36927382Evening primrose oil attenuates oxidative stress, inflammation, fibrosis, apoptosis, and ultrastructural alterations induced by metanil yellow in the liver of rat: a histological, immunohistochemical, and biochemical study
Fluted Gourd 📋 33402930Pumpkin seed oil alleviates oxidative stress and liver damage induced by sodium nitrate in adult rats: biochemical and histological approach
Frankincense Essential Oil 📋 ⛔31191820Frankincense Essential Oil Suppresses Melanoma Cancer Through Down Regulation of Bcl-2/Bax Cascade Signaling and Ameliorates Heptotoxicity via Phase I and II Drug Metabolizing Enzymes
Gamma-Linolenic Acid 📋✍⛔34281337γ-Linolenic Acid Prevents Lipid Metabolism Disorder in Palmitic Acid-Treated Alpha Mouse Liver-12 Cells by Balancing Autophagy and Apoptosis via the LKB1-AMPK-mTOR Pathway
Geraniin 📋 27591143Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA
Glycine 📋✍⛔33268508Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome
Goat Milk 📋 ⛔32752280Goat's Milk Intake Prevents Obesity, Hepatic Steatosis and Insulin Resistance in Mice Fed A High-Fat Diet by Reducing Inflammatory Markers and Increasing Energy Expenditure and Mitochondrial Content in Skeletal Muscle
Guggul 📋✍⛔34560545Myrrhanone B and Myrrhanol B from resin of Commipohora mukul exhibit hepatoprotective effects in-vivo
Guggulsterone 📋 37678053Kaempferol ameliorated alcoholic liver disease through inhibiting hepatic bile acid synthesis by targeting intestinal FXR-FGF15 signaling
Hemp Oil 📋✍⛔36734470Integration of transcriptomics and metabonomics revealed the protective effects of hemp seed oil against methionine-choline-deficient diet-induced non-alcoholic steatohepatitis in mice
Horse Chestnut 📋✍⛔34275854In vitro antioxidant potential and antiproliferative activity of Aesculus indica seed extract against hepatocellular carcinoma cell line
Horsetail Grass 📋✍⛔35789647Dose-Dependent Variation in Anticancer Activity of Hexane and Chloroform Extracts of Field Horsetail Plant on Human Hepatocarcinoma Cells
Hypericin 📋 31982488Hypericin attenuates nonalcoholic fatty liver disease and abnormal lipid metabolism via the PKA-mediated AMPK signaling pathway in vitro and in vivo
Iron 📋✍⛔36742167Iron as a therapeutic target in chronic liver disease
Isoflavones 📋✍⛔36923641Protective effects of isoflavones on alcoholic liver diseases: Computational approaches to investigate the inhibition of ALDH2 with isoflavone analogues
Jackfruit 📋 ⛔38201995Protective Effect of Artocarpus heterophyllus Lam. (Jackfruit) Polysaccharides on Liver Injury Induced by Cyclophosphamide in Mice
Jojoba Oil 📋✍⛔33481197Ameliorative effects of jojoba oil on fipronil-induced hepatorenal- and neuro-toxicity: the antioxidant status and apoptotic markers expression in rats
Kimchi 📋 ⛔38367426Kimchi attenuates endoplasmic reticulum stress-induced hepatic steatosis in HepG2 cells and C57BL/6N mice
Knotweed 📋✍⛔36683716In vivo recognition of bioactive substances of Polygonum multiflorum for protecting mitochondria against metabolic dysfunction-associated fatty liver disease
L-Histidine 📋✍⛔35267513Impact of Exogenous Treatment with Histidine on Hepatocellular Carcinoma Cells
L-Ornithine 📋✍⛔33454690THE EFFECTS OF L-ORNITINE AND L-ARGININE ON THE PROCESSES OF LIPID PEROXIDATION IN THE FUNCTIONAL LAYERS OF KIDNEYS ON THE BACKGROUND OF ACUTE TOXIC HEPATITIS
L-Proline 📋✍⛔20693968In vivo and In vitro effect of a nutrient mixture on human hepatocarcinoma cell line SK-HEP-1
L-Tyrosine 📋✍⛔37490119Dietary antioxidant quercetin overcomes the acquired resistance of Sorafenib in Sorafenib-resistant hepatocellular carcinoma cells through epidermal growth factor receptor signaling inactivation
Lavender Essential Oil 📋✍⛔28485153Antioxidant potential of essential oil from Lavandula angustifolia in in vitro and ex vivo cultured liver cells
Lemongrass Essential Oil 📋✍⛔28359199Protective Effect of Cymbopogon citratus Essential Oil in Experimental Model of Acetaminophen-Induced Liver Injury
Lentil 📋 ⛔36438775Antioxidative potential and ameliorative effects of green lentil ( Lens culinaris M.) sprouts against CCl4-induced oxidative stress in rats
Long Pepper 📋 ⛔36969834Amelioration of cyclophosphamide-induced DNA damage, oxidative stress, and hepato- and neurotoxicity by Piper longum extract in rats: The role of γH2AX and 8-OHdG
Mandarin 📋 38350206Citrus reticulata peel extract mitigates oxidative stress and liver injury induced by abamectin in rats
Millet 📋 36638159Millet Bran Protein Hydrolysate Displays the Anti-non-alcoholic Fatty Liver Disease Effect via Activating Peroxisome Proliferator-Activated Receptor γ to Restrain Fatty Acid Uptake
Minerals 📋 37608217Association between use of vitamin and mineral supplement and non-alcoholic fatty liver disease in hypertensive adults
Nattokinase 📋✍⛔31370114Nattokinase Crude Extract Inhibits Hepatocellular Carcinoma Growth in Mice
Neohesperidin 📋 32759940Neohesperidin enhances PGC-1α-mediated mitochondrial biogenesis and alleviates hepatic steatosis in high fat diet fed mice
Nuts 📋 ⛔37242277Effect of Nut Consumption on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Oats 📋 ⛔34965258The involvement of TGF-β1 /FAK/α-SMA pathway in the antifibrotic impact of rice bran oil on thioacetamide-induced liver fibrosis in rats
Oyster Mushrooms 📋 ⛔34855004Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model
Pantethine 📋✍⛔11425046The effects of pantethine on fatty liver and fat distribution
Papain 📋✍⛔26935541Comparative study of antitumor effects of bromelain and papain in human cholangiocarcinoma cell lines
Pau d'Arco 📋✍⛔25299819Ethanolic extract of Taheebo attenuates increase in body weight and fatty liver in mice fed a high-fat diet
Peanut 📋 ⛔15213031Frequent nut consumption and decreased risk of cholecystectomy in women
Pear 📋 ⛔31034714Pear Extract and Malaxinic Acid Reverse Obesity, Adipose Tissue Inflammation, and Hepatosteatosis in Mice
Pecan 📋 ⛔37299553Pecans and Its Polyphenols Prevent Obesity, Hepatic Steatosis and Diabetes by Reducing Dysbiosis, Inflammation, and Increasing Energy Expenditure in Mice Fed a High-Fat Diet
Pelargonidin 📋 31669604Pelargonidin Ameliorates Acetaminophen-Induced Hepatotoxicity in Mice by Inhibiting the ROS-induced Inflammatory Apoptotic Response
Phellodendron 📋✍⛔35463358Mechanism of Phellodendron and Anemarrhena Drug Pair on the Treatment of Liver Cancer Based on Network Pharmacology and Bioinformatics
Phosphatidylserine 📋✍⛔33977946DHA-enriched phosphatidylserine ameliorates non-alcoholic fatty liver disease and intestinal dysbacteriosis in mice induced by a high-fat diet
Phytoestrogens 📋 ⛔37719855Protective effect of phytoestrogens on nonalcoholic fatty liver disease in postmenopausal women
Phytosterols 📋 35683987The Role of Phytosterols in Nonalcoholic Fatty Liver Disease
Pine Needle Essential Oil 📋✍⛔19112901[Apoptosis and activity changes of telomerase induced by essential oil from pine needles in HepG2 cell line]
Potassium 📋✍⛔38635545Potassium affects the association between dietary intake of vitamin C and NAFLD among adults in the United States
Potato 📋 ⛔35403524The longitudinal associations between sweet potato intake and the risk of non-alcoholic fatty liver disease: the TCLSIH cohort study
Pregnenolone 📋✍⛔37259756Pregnenolone protects the liver against doxorubicin-induced cellular injury by anti-inflammatory, antioxidant, and antiapoptotic mechanisms: role of Keap1/Nrf2/HO-1 and P-glycoprotein
Prickly Pear 📋 ⛔36670975Molecular and Antioxidant Characterization of Opuntia robusta Fruit Extract and Its Protective Effect against Diclofenac-Induced Acute Liver Injury in an In Vivo Rat Model
Pumpkin 📋 ⛔28634059A pumpkin polysaccharide induces apoptosis by inhibiting the JAK2/STAT3 pathway in human hepatoma HepG2 cells
Pumpkin Seed Oil 📋✍⛔26405765Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil
Rehmannia 📋✍⛔16874858Hot Water-Extracted Lycium Barbarum and Rehmannia Glutinosa Inhibit Proliferation and Induce Apoptosis of Hepatocellular Carcinoma Cells
Rose 📋 37797686Evaluation of the flavonol-rich fraction of Rosa damascena in an animal model of liver fibrosis by targeting the expression of fibrotic cytokines, antioxidant/oxidant ratio and collagen cross-linking
Rosehip 📋✍⛔37959727Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in Hepatocytes
Rye 📋 ⛔35091747Plasma Alkylresorcinol Metabolite, a Biomarker for Whole-Grain Intake, Is Inversely Associated with Risk of Nonalcoholic Fatty Liver Disease in a Case-Control Study of Chinese Adults
Sage 📋✍⛔27930987Antiproliferative effects of extracts from Salvia officinalis L. and Saliva miltiorrhiza Bunge on hepatocellular carcinoma cells
Star Anise 📋✍⛔30700011Hypolipogenic Effect of Shikimic Acid Via Inhibition of MID1IP1 and Phosphorylation of AMPK/ACC
Stevia 📋✍⛔36552704Stevia and Stevioside Attenuate Liver Steatosis through PPARα-Mediated Lipophagy in db/db Mice Hepatocytes
Sugarcane 📋 ⛔29322133Anti-fibrotic activity of polyphenol-enriched sugarcane extract in rats via inhibition of p38 and JNK phosphorylation
Tea Polysaccharides 📋 23623843Protective effects of Keemun black tea polysaccharides on acute carbon tetrachloride-caused oxidative hepatotoxicity in mice
Terpenoids 📋 36615471Terpenoids: Natural Compounds for Non-Alcoholic Fatty Liver Disease (NAFLD) Therapy
Theobromine 📋✍⛔33290156Theobromine ameliorates nonalcoholic fatty liver disease by regulating hepatic lipid metabolism via mTOR signaling pathway in vivo and in vitro
Thyme Essential Oil 📋 ⛔38034947Comparison of the virucidal efficacy of essential oils (cinnamon, clove, and thyme) against hepatitis A virus in suspension and on food-contact surfaces
Trans-Resveratrol 📋 34835933Combination of Trans-Resveratrol and ε-Viniferin Induces a Hepatoprotective Effect in Rats with Severe Acute Liver Failure via Reduction of Oxidative Stress and MMP-9 Expression
Vitamin B2 📋✍⛔36160891Riboflavin ameliorates mitochondrial dysfunction via the AMPK/PGC1α/HO‑1 signaling pathway and attenuates carbon tetrachloride‑induced liver fibrosis in rats
Vitamin B5 📋✍⛔1810066[The use of pantothenic acid preparations in treating patients with viral hepatitis A]
Vitamin K 📋✍⛔34444675The Role of Vitamin K in Cholestatic Liver Disease
Vitamin K1 📋✍⛔32221088Effect of vitamin K1 on survival of patients with chronic liver failure: A retrospective cohort study
Vitamin K2 mk-7 📋✍ 36358523Vitamin K2 (MK-7) Intercepts Keap-1/Nrf-2/HO-1 Pathway and Hinders Inflammatory/Apoptotic Signaling and Liver Aging in Naturally Aging Rat
Water Chestnut 📋✍⛔35208513Evaluation of Dose-Dependent Obesity and Diabetes-Related Complications of Water Chestnut (Fruit of Trapa japonica) Extracts in Type II Obese Diabetic Mice Induced by 45% Kcal High-Fat Diet
Watermelon 📋 ⛔34841269Watermelon rind ethanol extract exhibits hepato-renal protection against lead induced-impaired antioxidant defenses in male Wistar rats
Wheat 📋 ⛔35091747Plasma Alkylresorcinol Metabolite, a Biomarker for Whole-Grain Intake, Is Inversely Associated with Risk of Nonalcoholic Fatty Liver Disease in a Case-Control Study of Chinese Adults
White Fungus 📋 35723304Tremella fuciformis Crude Polysaccharides Attenuates Steatosis and Suppresses Inflammation in Diet-Induced NAFLD Mice
Wood Ear Mushrooms 📋 ⛔34681485Auricularia auricula Melanin Protects against Alcoholic Liver Injury and Modulates Intestinal Microbiota Composition in Mice Exposed to Alcohol Intake
Yiang Yiang Essential Oil 📋 ⛔31956259Antiviral Activity of Cananga odorata Against Hepatitis B Virus